Research Article
Vitamin D and Nonskeletal Complications among Egyptian Sickle Cell Disease Patients
Table 5
Association between VDD, clinical course, and complications of SCD.
| | Variable | Normal Group (n=32) | Deficient Group (n=48) | P-value |
| | Blood transfusion: n (%) (n=69) | 30 (43.4) | 39 (56.6) | 0.475 |
| | Age at blood transfusion (years) | 2.3 ± 1.9 | 1.6 ±1.0 | 0.351 |
| | Frequency of blood transfusion/ Last year | 3.6 ± 2.8 | 5.4 ± 3.5 | 0.021 |
| | Positive VOC/ Last year: n (%) (n=68) | 24 (35.2) | 44 (64.8) | 0.032 |
| | Degree of VOC: n (%) | | | 0.732 | | Mild (n=41) | 13 (31.7) | 28 (68.3) | | | Moderate (n= 21) | 10 (47.6) | 11 (52.4) | | | Severe (n= 6) | 1 (16.6) | 5 (83.4) | |
| | Hospital admission/ Last year: n (%) (n=44) | 14 (31.8) | 30 (68.2) | 0.012 |
| | Bone fracture: n (%) (n=8) | 1 (12.5) | 7 (87.5) | 0.034 |
| | Recurrent infection: n (%) (n= 36) | 7 (19.5) | 29 (80.5) | 0.036 |
| | Viral hepatitis (B&C): n (%) (n=12) | 5 (41.6) | 7 (58.4) | 0.219 |
| | Pulmonary hypertension: n (%)(n=11) | 3 (27.3) | 8 (72.7) | 0.068 |
| | Diabetes Mellitus: n (%) (n=4) | 2 (50) | 2 (50) | 0.721 |
| | Abnormal TCD: n (%) (n= 2) | 1 (50) | 1 (50) | 0.834 |
| | Gall Bladder stones: n ( %) (n= 3) | 1 (33.3) | 2 (66.7) | 0.059 |
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n = number; SD = standard deviation; VOC = vasoocclusive crisis; TCD= transcranial Doppler. Bold values indicate statistical significance.
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