Research Article
Effect of Imatinib on Bone Marrow Morphology and Angiogenesis in Chronic Myeloid Leukemia
Table 6
Comparison of bone marrow morphological changes between the present study and previous studies.
| | Morphological parameters | BH Srinivas et al. | Present study | | (2012) | (2017) |
| | | Initial | 8 months of follow-up | Initial | Follow-up |
| | Increased cellularity | 100% | 20.4% | 100% | 13.8% |
| | M:E ratio > 4:1 | 100% | 35.1% | 100% | 27.6% |
| | Blast > 5 | 17% | 10.6% | 27.6% | 3.4% |
| | Basophil >1 | 61% | 25.5% | 93.1% | 41.3% |
| | Abnormal megakaryocytes | 100% | 27.5% | 100% | 24.1% |
| | MMR score | | | | | | ≤ 1 | | 66.34% | | 86.20% | | ≥2 | | 33.66% | | 13.79% |
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M:E ratio: myeloid: erythroid ratio and MMR: marrow morphological response.
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