Enhanced Hypercoagulability in Sickle Cell Anaemia Patients with Chronic Leg Ulcers
Table 4
Association between selected patients’ characteristics and coagulation profile.
Parameter
Age
Duration of CLU
Frequency of CLU
Hb concentration
Platelet count
Age
R
1.000
0.351
0.108
0.182
−0.349
P
—
0.015
0.455
0.028
0.000
Hb
R
0.182
−0.331
−0.204
1.000
−0.664
P
0.028
0.021
0.156
—
0.000
Fibrinogen
R
0.096
0.131
−0.104
−0.008
−0.037
P
0.253
0.374
0.471
0.922
0.659
D-dimer
R
0.065
−0.062
−0.024
−0.233
0.126
P
0.440
0.676
0.867
0.005
0.130
PT
R
−0.076
0.035
−0.162
−0.233
0.241
P
0.360
0.815
0.260
0.005
0.004
APTT
R
−0.096
−0.181
−0.086
0.185
−0.120
P
0.253
0.219
0.552
0.026
0.149
Platelets
R
−0.349
−0.166
−0.311
−0.664
1.000
P
0.000
0.261
0.028
0.000
—
r: coefficient of correlation; CLU: chronic leg ulcer; Hb: haemoglobin; PT: prothrombin time; aPTT: activated partial thromboplastin time, Correlation is significant at the 0.05 level.