Research Article
Laboratory Biomarkers, Cerebral Blood Flow Velocity, and Intellectual Function in Children with Sickle Cell Disease
| | | N (%) | Mean (SD) | Range |
| | Gender | | | | | Male | 20 (53) | | | | Female | 18 (47) | | | | Age (years) | | 7.19 (1.61) | 4–11 | | Maternal education (years) | | 13.25 (1.93) | 11–18 | | SB-V | | | | | ABIQ (standard score) | | 91.79 (11.97) | 70–115 | | Nonverbal (scaled score) | | 8.63 (2.57) | 3–13 | | Verbal (scaled score) | | 8.63 (2.64) | 3–14 | | Hydroxyurea (yes) | 10 (26) | | | | MRI (yes) | 12 (32) | | | | TCD (cm/sec) | | | | | Highest value | | 131 (22) | 92–178 | | Right MCA | | 123 (25) | 82–178 | | Left MCA | | 125 (22) | 68–175 | | Right ACA | | 54 (12) | 30–91 | | Left ACA | | 55 (14) | 33–88 | | Right DICA | | 95 (16) | 72–153 | | Left DICA | | 96 (20) | 71–154 | | Right PCA | | 62 (13) | 42–94 | | Left PCA | | 64 (14) | 39–96 | | Hgb (g/dL) | | 8.25 (1.00) | 6.30–11.00 | | HbF (%) | | 11.88 (6.81) | 1.40–28.90 | | WBC (103/μL) | | 11.06 (3.02) | 6.50–19.10 | | CRP (ng/ml) | | 1417 (1423) | 236–5866 | | ANC (103/μL) | | 5.15 (3.04) | 1.10–14.80 | | LDH (U/L) | | 584 (164) | 279–972 | | Reticulocyte (%) | | 10.10 (4.72) | 2.80–23.00 | | Bilirubin (mg/dL) | | 2.87 (1.89) | 1.00–10.80 | | AST (U/L) | | 46.64 (12.58) | 25.00–72.00 | | EPO | | 100 (91) | 27–485 | | TF (pg/ml) | | 248 (111) | 78–549 | | TAT (ng/ml) | | 78.60 (133.72) | 0.10–500.00 | | sVCAM-1 (ng/ml) | | 1566 (596) | 838–4214 | | 11-dTXB2 (pg/ml) | | 4556 (2687) | 285–10000 | | Platelet count (103/μL) | | 428 (114) | 152–705 |
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