Advances in Hematology / 2020 / Article / Tab 1

Clinical Study

Assessing the Performance of Extended Half-Life Coagulation Factor VIII, FC Fusion Protein by Using Chromogenic and One-Stage Assays in Saudi Hemophilia A Patients

Table 1

The comparison between the one-stage assay versus chromogenic assay for the measurement of factor VIII levels in the study population.

Time of sample collectionNOne-stage assay†Chromogenic assay†Mean differenceSE value95% CI

>1 day110.22 (0.23)0.33 (0.31)−0.100.030.014−0.18 to −0.27
>2 days100.08 (0.07)0.13 (0.10)−0.050.0180.026−0.09 to −0.007
>3 days100.02 (0.03)0.09 (0.077)−0.060.020.024−0.11 to −0.01
>4 days110.02 (0.02)0.07 (0.06)−0.050.0180.022−0.09 to −0.008
>5 days80.01 (0.004)0.07 (0.08)−0.060.030.077−0.13 to −0.008
Others60.1 (0.11)0.13 (0.16)−0.030.0190.105−0.08 to 0.011
All samples560.08 (0.13)0.14 (0.18)−0.060.08˂0.001−0.08 to −0.04

N = number of samples evaluated; † data reported in mean (standard deviation); SE = standard error; CI = confidence interval; others: includes samples collected after more than one week.

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