Research Article

Relationship between Higher Atherogenic Index of Plasma and Oxidative Stress of a Group of Patients Living with Sickle Cell Anemia in Cameroon

Table 3

Effect of lipid profile on some markers of oxidative stress.

Lipid profileSOD (UI/mg protein)GsH (µM)GPx (UI/mg protein)FRAP (µM)CAT (UI/mg protein)MDA (µM)

TC (mg/dl)Normal1.01 ± 1.004.62 ± 0.340.64 ± 1.03272.12 ± 12.52.26 ± 0.550.97 ± 0.77
Abnormal0.78 ± 0.723.80 ± 1.340.52 ± 0.27238.59 ± 10.51.10 ± 0.561.30 ± 0.2

TG (mg/dl)Normal0.95 ± 0.954.67 ± 0.20.59 ± 0.83275.42 ± 16.471.14 ± 0.591.10 ± 0.17
Abnormal0.71 ± 0.484.10 ± 0.40.55 ± 0.26200.34 ± 9.681.29 ± 0.422.15 ± 0.2

LDL-C (mg/dl)Normal0.82 ± 0.104.48 ± 0.280.74 ± 0.23234.50 ± 71.911.26 ± 0.100.89 ± 0.16
Abnormal0.93 ± 0.133.71 ± 0.240.50 ± 0.03266.48 ± 78.551.13 ± 0.071.26 ± 1.46

HDL-C (mg/dl)Normal0.90 ± 0.153.66 ± 0.320.53 ± 0.07236.46 ± 54.871.18 ± 0.100.67 ± 0.14
Abnormal0.89 ± 0.114.35 ± 0.240.59 ± 0.09260.12 ± 9.701.17 ± 0.071.24 ± 0.16

Results are expressed as mean ± SD. indicates the values are statistically significant in the same column. . GsH = reduced glutathione, SOD = superoxide dismutase, FRAP = ferric reducing antioxidant power, GPx = glutathione peroxidase; LDL-C = low-density lipoprotein, TC = total cholesterol, TG = triglyceride, and HDL-C = high-density lipoprotein.