Research Article

Ibrutinib plus Obinutuzumab as Frontline Therapy for Chronic Lymphocytic Leukemia Is Associated with a Lower Rate of Infusion-Related Reactions and with Sustained Remissions after Ibrutinib Discontinuation: A Single-Arm, Open-Label, Phase 1b/2 Clinical Trial NCT0231576

Table 3

Summary of the results.

Number of patients (%)
Ibrutinib plus obinutuzumab (n = 32)

Primary endpoints
ORR32 (100)
Secondary endpoints
PFSNot reached
TFSNot reached
OS32 (100)
CR9 (28.5)
MRDneg4 (12.5)
PR20 (62)
SD0 (0)
PD3 (9)