Hepatitis B Virus Infection and the Kidney: Renal Abnormalities in HBV Patients, Antiviral Drugs Handling, and Specific Follow-Up

Table 4

Drug dosing recommendations for lamivudine in CHB patients with CKD.

eGFR (mL/Min)	Dosage recommended
	First dose	Maintenance
≥90	100 mg	100 mg/day
<90–60	100 mg	100 mg/day
<60–30	100 mg	50 mg/day
<30–15	100 mg	25 mg/day
<15	35 mg	10–15 mg/day
HD^*	35 mg	10–15 mg/day
CAPD	35 mg	10 mg/day

 ^*On hemodialysis days, lamivudine should be administered after the session.
eGFR: estimated glomerular filtration rate.
Source: http://www.sitegpr.com/.