Beta2-Adrenergic Receptor Gene Polymorphisms in Egyptian Patients with Acute Myocardial Infarction
Table 4
Haplotype frequencies of ADRB2 gene polymorphisms in patients and controls according to the copy number.
Variables
Patients ()
Controls ()
value
Crude OR (95% CI)
Adjusted& OR (95% CI)
Arg16/Gln27
Negative
28 (41.2)
29 (38.7)
0.146
0.703
1.0
1.0
1 copy
30 (44.1)
40 (53.3)
0.7 (0.3–1.5)
0.4 (0.1–1.66)
2 copies
10 (14.7)
6 (8.0)
1.7 (0.5–5.3)
0.5 (0.07–3.9)
Gly16/Gln27
Negative
39 (57.4)
46 (61.4)
3.378
0.066
1.0
1.0
1 copy
17 (25.0)
28 (37.3)
0.7 (0.3–1.4)
0.3 (0.1–1.08)
2 copies
12 (17.6)
1 (1.3)
14.1 (1.7–113)*
20.4 (1.4–296)*
Gly16/Glu27
Negative
34 (50.0)
22 (29.3)
4.012
0.045*
1.0
1.0
1 copy
23 (33.8)
38 (50.7)
0.3 (0.1–0.8) *
0.5 (0.17–1.5)
2 copies
11 (16.2)
15 (20.0)
0.4 (0.1–1.2)
1.9 (0.47–8.2)
Values are shown as number (%). Chi-square () for trend was used. OR (95% CI): odds ratio and confidence interval. &Adjusted for confounding factors. *Statistically significant at .
