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Advances in Medicine
Volume 2016, Article ID 3194010, 6 pages
http://dx.doi.org/10.1155/2016/3194010
Clinical Study

Efficacy of Synbiotics for Treatment of Bacillary Dysentery in Children: A Double-Blind, Randomized, Placebo-Controlled Study

Infectious Diseases Research Centre (IDRC), Arak University of Medical Sciences, Arak, Iran

Received 21 April 2016; Revised 29 August 2016; Accepted 9 October 2016

Academic Editor: Aliya Naheed

Copyright © 2016 Manijeh Kahbazi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. K. Niyogi, “Shigellosis,” Journal of Microbiology, vol. 43, no. 2, pp. 133–143, 2005. View at Google Scholar · View at Scopus
  2. A. V. Sangeetha, S. C. Parija, J. Mandal, and S. Krishnamurthy, “Clinical and microbiological profiles of Shigellosis in children,” Journal of Health, Population and Nutrition, vol. 32, no. 4, pp. 580–586, 2014. View at Google Scholar · View at Scopus
  3. P. Bardhan, A. S. G. Faruque, A. Naheed, and D. A. Sack, “Decrease in shigellosis-related deaths without shigella spp.- specific interventions, Asia,” Emerging Infectious Diseases, vol. 16, no. 11, pp. 1718–1723, 2010. View at Publisher · View at Google Scholar · View at Scopus
  4. E. Scallan, T. F. Jones, A. Cronquist et al., “Factors associated with seeking medical care and submitting a stool sample in estimating the burden of foodborne illness,” Foodborne Pathogens and Disease, vol. 3, no. 4, pp. 432–438, 2006. View at Publisher · View at Google Scholar · View at Scopus
  5. A. L. Shane, N. A. Tucker, J. A. Crump, E. D. Mintz, and J. A. Painter, “Sharing Shigella: risk factors for a multicommunity outbreak of shigellosis,” Archives of Pediatrics & Adolescent Medicine, vol. 157, no. 6, pp. 601–603, 2003. View at Publisher · View at Google Scholar · View at Scopus
  6. A. S. Neish, “Microbes in Gastrointestinal Health and Disease,” Gastroenterology, vol. 136, no. 1, pp. 65–80, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. M. J. Kullen and J. Bettler, “The delivery of probiotics and prebiotics to infants,” Current Pharmaceutical Design, vol. 11, no. 1, pp. 55–74, 2005. View at Publisher · View at Google Scholar · View at Scopus
  8. S. Michail, F. Sylvester, G. Fuchs, and R. Issenman, “Clinical efficacy of probiotics: review of the evidence with focus on children,” Journal of Pediatric Gastroenterology and Nutrition, vol. 43, no. 4, pp. 550–557, 2006. View at Publisher · View at Google Scholar · View at Scopus
  9. H. Szajewska, A. Guarino, I. Hojsak et al., “Use of probiotics for management of acute gastroenteritis: a position paper by the ESPGHAN working group for probiotics and prebiotics,” Journal of Pediatric Gastroenterology and Nutrition, vol. 58, no. 4, pp. 531–539, 2014. View at Publisher · View at Google Scholar · View at Scopus
  10. K. Arunachalam, H. S. Gill, and R. K. Chandra, “Enhancement of natural immune function by dietary consumption of Bifidobacterium lactis (HN019),” European Journal of Clinical Nutrition, vol. 54, no. 3, pp. 263–267, 2000. View at Publisher · View at Google Scholar · View at Scopus
  11. M. D. Cabana, A. L. Shane, C. Chao, and M. Oliva-Hemker, “Probiotics in primary care pediatrics,” Clinical Pediatrics, vol. 45, no. 5, pp. 405–410, 2006. View at Publisher · View at Google Scholar · View at Scopus
  12. V. De Preter, T. Vanhoutte, G. Huys, J. Swings, P. Rutgeerts, and K. Verbeke, “Effect of lactulose and Saccharomyces boulardii administration on the colonic urea-nitrogen metabolism and the bifidobacteria concentration in healthy human subjects,” Alimentary Pharmacology and Therapeutics, vol. 23, no. 7, pp. 963–974, 2006. View at Publisher · View at Google Scholar · View at Scopus
  13. R. N. Fedorak and K. L. Madsen, “Probiotics and prebiotics in gastrointestinal disorders,” Current Opinion in Gastroenterology, vol. 20, no. 2, pp. 146–155, 2004. View at Publisher · View at Google Scholar · View at Scopus
  14. H. Link-Amster, F. Rochat, K. Y. Saudan, O. Mignot, and J. M. Aeschlimann, “Modulation of a specific humoral immune response and changes in intestinal flora mediated through fermented milk intake,” FEMS Immunology and Medical Microbiology, vol. 10, no. 1, pp. 55–63, 1994. View at Publisher · View at Google Scholar · View at Scopus
  15. S. Michail and F. Abernathy, “Lactobacillus plantarum reduces the in vitro secretory response of intestinal epithelial cells to enteropathogenic Escherichia coli infection,” Journal of Pediatric Gastroenterology and Nutrition, vol. 35, no. 3, pp. 350–355, 2002. View at Publisher · View at Google Scholar · View at Scopus
  16. S. J. Allen, B. Okoko, E. Martinez, G. Gregorio, and L. F. Dans, “Probiotics for treating infectious diarrhoea,” Cochrane Database of Systematic Reviews, no. 2, Article ID CD003048, 2004. View at Google Scholar · View at Scopus
  17. H. Szajewska and J. Z. Mrukowicz, “Probiotics in the treatment and prevention of acute infectious diarrhea in infants and children: a systematic review of published randomized, double-blind, placebo-controlled trials,” Journal of Pediatric Gastroenterology and Nutrition, vol. 33, supplement 2, pp. S17–S25, 2001. View at Publisher · View at Google Scholar · View at Scopus
  18. G. T. Macfarlane, H. Steed, and S. Macfarlane, “Bacterial metabolism and health-related effects of galacto-oligosaccharides and other prebiotics,” Journal of Applied Microbiology, vol. 104, no. 2, pp. 305–344, 2008. View at Publisher · View at Google Scholar · View at Scopus
  19. J. E. Idanpaan-Heikkila, “WHO guidelines for good clinical practice (GCP) for trials on pharmaceutical products: responsibilities of the investigator,” Annals of Medicine, vol. 26, no. 2, pp. 89–94, 1994. View at Publisher · View at Google Scholar · View at Scopus
  20. S. Koletzko and S. Osterrieder, “Acute infectious diarrhea in children,” Deutsches Ärzteblatt International, vol. 106, no. 33, pp. 539–548, 2009. View at Publisher · View at Google Scholar · View at Scopus
  21. A. C. Senok, A. Y. Ismaeel, and G. A. Botta, “Probiotics: facts and myths,” Clinical Microbiology and Infection, vol. 11, no. 12, pp. 958–966, 2005. View at Publisher · View at Google Scholar · View at Scopus
  22. B. Wallace, “Clinical use of probiotics in the pediatric population,” Nutrition in Clinical Practice, vol. 24, no. 1, pp. 50–59, 2009. View at Publisher · View at Google Scholar
  23. A. Işlek, E. Sayar, A. Yilmaz, B. O. Baysan, D. Mutlu, and R. Artan, “The role of Bifidobacterium lactis B94 plus inulin in the treatment of acute infectious diarrhea in children,” The Turkish Journal of Gastroenterology, vol. 25, no. 6, pp. 628–633, 2014. View at Publisher · View at Google Scholar · View at Scopus
  24. S. B. Freedman, D. Pasichnyk, K. J. L. Black et al., “Gastroenteritis therapies in developed countries: systematic review and meta-analysis,” PLoS ONE, vol. 10, no. 6, article e0128754, 2015. View at Publisher · View at Google Scholar · View at Scopus
  25. J. A. Hawrelak, D. L. Whitten, and S. P. Myers, “Is Lactobacillus rhamnosus GG effective in preventing the onset of antibiotic-associated diarrhoea: a systematic review,” Digestion, vol. 72, no. 1, pp. 51–56, 2005. View at Publisher · View at Google Scholar · View at Scopus
  26. B. C. Johnston, J. Z. Goldenberg, P. O. Vandvik, X. Sun, and G. H. Guyatt, “Probiotics for the prevention of pediatric antibiotic-associated diarrhea,” The Cochrane Database of Systematic Reviews, no. 11, Article ID CD004827, 2011. View at Google Scholar · View at Scopus
  27. M. Pham, D. A. Lemberg, and A. S. Day, “Probiotics: sorting the evidence from the myths,” The Medical Journal of Australia, vol. 188, no. 5, pp. 304–308, 2008. View at Google Scholar · View at Scopus
  28. C. C. Butler, D. Duncan, and K. Hood, “Does taking probiotics routinely with antibiotics prevent antibiotic associated diarrhoea?” BMJ (Online), vol. 344, article e682, 2012. View at Publisher · View at Google Scholar · View at Scopus
  29. S. J. Allen, E. G. Martinez, G. V. Gregorio, and L. F. Dans, “Probiotics for treating acute infectious diarrhoea,” The Cochrane Database of Systematic Reviews, no. 11, Article ID CD003048, 2010. View at Google Scholar · View at Scopus
  30. E. C. Dinleyici, N. Dalgic, S. Guven et al., “Lactobacillus reuteri DSM 17938 shortens acute infectious diarrhea in a pediatric outpatient setting,” Jornal de Pediatria, vol. 91, no. 4, pp. 392–396, 2015. View at Publisher · View at Google Scholar · View at Scopus
  31. J.-F. Rossignol, N. Lopez-Chegne, L. M. Julcamoro, M. E. Carrion, and M. C. Bardin, “Nitazoxanide for the empiric treatment of pediatric infectious diarrhea,” Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 106, no. 3, pp. 167–173, 2012. View at Publisher · View at Google Scholar · View at Scopus
  32. H. Ashraf, D. Mahalanabis, A. K. Mitra, S. Tzipori, and G. J. Fuchs, “Hyperimmune bovine colostrum in the treatment of shigellosis in children: a double-blind, randomized, controlled trial,” Acta Paediatrica, vol. 90, no. 12, pp. 1373–1378, 2001. View at Publisher · View at Google Scholar · View at Scopus
  33. H. Vinh, V. T. C. Anh, N. D. Anh et al., “A multi-center randomized trial to assess the efficacy of gatifloxacin versus ciprofloxacin for the treatment of shigellosis in Vietnamese children,” PLoS Neglected Tropical Diseases, vol. 5, no. 8, Article ID e1264, 2011. View at Publisher · View at Google Scholar · View at Scopus
  34. C.-C. Chen, M.-S. Kong, M.-W. Lai et al., “Probiotics have clinical, microbiologic, and immunologic efficacy in acute infectious diarrhea,” The Pediatric Infectious Disease Journal, vol. 29, no. 2, pp. 135–138, 2010. View at Publisher · View at Google Scholar · View at Scopus
  35. E. C. A. Dinleyici and Y. Vandenplas, “Lactobacillus reuteri DSM 17938 effectively reduces the duration of acute diarrhoea in hospitalised children,” Acta Paediatrica, vol. 103, no. 7, pp. e300–e305, 2014. View at Publisher · View at Google Scholar · View at Scopus
  36. R. Francavilla, L. Polimeno, A. Demichina et al., “Lactobacillus reuteri strain combination in Helicobacter pylori infection: a randomized, double-blind, placebo-controlled study,” Journal of Clinical Gastroenterology, vol. 48, no. 5, pp. 407–413, 2014. View at Publisher · View at Google Scholar · View at Scopus
  37. S. Guandalini, L. Pensabene, M. A. Zikri et al., “Lactobacillus GG administered in oral rehydration solution to children with acute diarrhea: a multicenter European trial,” Journal of Pediatric Gastroenterology and Nutrition, vol. 30, no. 1, pp. 54–60, 2000. View at Publisher · View at Google Scholar · View at Scopus
  38. Z. Weizman, G. Asli, and A. Alsheikh, “Effect of a probiotic infant formula on infections in child care centers: comparison of two probiotic agents,” Pediatrics, vol. 115, no. 1, pp. 5–9, 2005. View at Publisher · View at Google Scholar · View at Scopus
  39. G. J. Oudhuis, D. C. J. J. Bergmans, and A. Verbon, “Probiotics for prevention of nosocomial infections: efficacy and adverse effects,” Current Opinion in Critical Care, vol. 17, no. 5, pp. 487–492, 2011. View at Publisher · View at Google Scholar · View at Scopus