CYP4F2 (rs2108622) Gene Polymorphism Association with Age-Related Macular Degeneration

Table 8

Binomial logistic regression analysis of the CYP4F2 (1347C>T; V433M) rs2108622 in males and females with eAMD and in the control group.

Model	Genotype	OR (95% CI)	value	AIC
Female
Codominant	T/T	0.130 (0.016; 1.036)	0.054	386.317
	T/C	1.098 (0.674; 1.788)	0.707
Dominant	T/C + T/T	0.958 (0.595; 1.542)	0.859	390.898
Recessive	T/T	0.125 (0.016; 0.988)	0.049	384.458
Overdominant	T/C	1.201 (0.741; 1.945)	0.458	390.379
Additive	—	1.220 (0.805; 1.850)	0.348	390.041
Male
Codominant	T/T	0.645 (0.182; 2.282)	0.497	153.306
	T/C	0.617 (0.274; 1.389)	0.243
Dominant	T/C + T/T	0.623 (0.290; 1.339)	0.225	151.311
Recessive	T/T	0.811 (0.244; 2.696)	0.733	152.676
Overdominant	T/C	0.672 (0.311; 1.452)	0.312	151.767
Additive	—	1.357 (0.770; 2.392)	0.291	151.666