TY - JOUR A2 - Tang, Weihua AU - Paşcalău, Violeta AU - Popescu, Violeta AU - Popescu, George L. AU - Dudescu, Mircea C. AU - Borodi, Gheorghe AU - Dinescu, Adrian M. AU - Moldovan, Marioara PY - 2013 DA - 2013/12/31 TI - Obtaining and Characterizing Alginate/k-Carrageenan Hydrogel Cross-Linked with Adipic Dihydrazide SP - 380716 VL - 2013 AB - The aim of this paper is obtaining and characterizing hydrogels based on different ratios of oxidized alginate (oA) and k-carrageenan (C), chemically cross-linked with adipic dihydrazide (adh). The alginate (A) was first oxidized with sodium metaperiodate in order to transform it into the dialdehyde derivative, a more reactive compound than alginate. A known procedure for oxidation of alginate with sodium metaperiodate in ethanol-water in order to improve alginate reactivity by transforming the hydroxyl end-groups into dialdehyde was used, preceded by a partially cleavage of the alginate chains. In the second stage, the mixture of dialdehydic derivative of oxidized alginate, k-carrageenan and glycerol subjected to reaction with adipic dihydrazide leads to a Semi-Interpenetrated Network covalently cross-linked alginate/k-carrageenan hydrogel (oACadh), based on the dihydrazone compound which is responsible for the chemical cross-linking. Pure alginate, k-carrageenan, oxidized alginate, adipic dihydrazide and the cross-linked hydrogel were characterized by: FTIR, XRD, and SEM. SN - 1687-8434 UR - https://doi.org/10.1155/2013/380716 DO - 10.1155/2013/380716 JF - Advances in Materials Science and Engineering PB - Hindawi Publishing Corporation KW - ER -