Figure 10: Effects of various composite powders modification (exchange of silica filer with HA whiskers %) on THP-1 cell viability. THP-1 cells were treated with different concentrations of HA or CC (0.05–0.5 mg/ml) for 48 h, and then cell viability was assessed by the MTT assay. Results are expressed as percentages of untreated cultures. Data are the mean ± SEM from five separate experiments. Statistically significant differences were evaluated by one-way ANOVA, followed by Newman-Keuls post hoc test. , , and significant differences in comparison to untreated cells.