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Volume 2012, Article ID 608658, 7 pages
Clinical Study

Evaluation of Hematological Parameters in Partial Exchange and Packed Cell Transfusion in Treatment of Severe Anemia in Pregnancy

1Department of Obstetrics & Gynecology, Hamdard Institute of Medical Sciences & Research, New Delhi 110062, India
2The Department of Mathematics & Statistics, The University of the West Indies, St. Augustine Campus, Trinidad and Tobago
3Medical Research Centre and Cardiology, CCS Department, Hamad Medical Corporation (HMC), Doha, Qatar
4Department of Obstetrics & Gynecology, Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi 110029, India

Received 25 January 2012; Revised 11 March 2012; Accepted 13 March 2012

Academic Editor: Eitan Fibach

Copyright © 2012 Sudha Salhan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objectives. Anemia is a major public health problem throughout the world which assumes prominence in pregnant mothers. Patients with severe anemia continue to present themselves at term or in labor. This study was conducted to compare the improvements in hematological parameters of patients receiving partial exchange blood transfusion and transfusion of packed cells without exchange. Methods. One hundred and twenty-five severely anemic antenatal mothers were admitted from outpatient service. Partial exchange transfusion was given to sixty-six patients while fifty-nine received transfusion of packed cells with frusemide cover. Results. The two groups were comparable in terms of age, height, weight, religion, diet, education, occupation of self and husband, and income. Hemoglobin level in Group 1 was comparatively less than Group 2 at prelevel ( versus , ) and postlevel ( versus , ), respectively, but there was no significant difference between the two modes of transfusion ( versus , ). Conclusion. The study produced an equally significant improvement in hematological parameters in partial exchange and packed cell transfusion. Platelet counts were significantly less in partial exchange as compared with packed cell transfusion.