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Anemia
Volume 2014, Article ID 640203, 6 pages
http://dx.doi.org/10.1155/2014/640203
Research Article

Correlation between Plasma Interleukin-3, the α/β Globin Ratio, and Globin mRNA Stability

1Biochemistry Department, Pasteur Institute of Iran, Pasteur Street, No. 69, Tehran 1316943551, Iran
2Molecular Medicine Department, Pasteur Institute of Iran, Pasteur Street, No. 69, Tehran 1316943551, Iran
3Immunology Department, Pasteur Institute of Iran, Pasteur Street, No. 69, Tehran 1316943551, Iran
4Department of Epidemiology, Pasteur Institute of Iran, Pasteur Street, No. 69, Tehran 1316943551, Iran

Received 27 August 2014; Accepted 25 October 2014; Published 18 November 2014

Academic Editor: Aurelio Maggio

Copyright © 2014 S. Rouhi Dehnabeh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. D. A. Day and M. F. Tuite, “Post-transcriptional gene regulatory mechanisms in eukaryotes: an overview,” Journal of Endocrinology, vol. 157, no. 3, pp. 361–371, 1998. View at Publisher · View at Google Scholar · View at Scopus
  2. S. Khatami, S. R. Dehboneh, S. Sadeghi et al., “Globin chain synthesis is a useful complementary tool in the differential diagnosis of thalassemias,” Hemoglobin, vol. 31, no. 3, pp. 333–341, 2007. View at Publisher · View at Google Scholar · View at Scopus
  3. A. Villegas, J. Sanchez, F. Gonzalez et al., “Red blood cell phenotypes in α thalassemias in the Spanish population,” Hematologica, vol. 83, no. 2, pp. 99–103, 1998. View at Google Scholar
  4. P. C. Giordano, P. van Delft, D. Batelaan, C. L. Harteveld, and L. F. Bernini, “Haemoglobinopathy analyses in the netherlands: a report of an in vitro globin chain biosynthesis survey using a rapid, modified method,” Clinical and Laboratory Haematology, vol. 21, no. 4, pp. 247–255, 1999. View at Publisher · View at Google Scholar · View at Scopus
  5. D. Reinhardt, R. Ridder, W. Kugler, and A. Pekrun, “Post-transcriptional effects of interleukin-3, interferon-γ, erythropoietin and butyrate on in vitro hemoglobin chain synthesis in congenital hemolytic anemia,” Haematologica, vol. 86, no. 8, pp. 791–800, 2001. View at Google Scholar · View at Scopus
  6. http://www.rightdiagnosis.com/medical/interleukin_3.htm.
  7. http://www.biocarta.com/genes/CytokinesChemokines.asp.
  8. A. D. Sheftel, A. B. Mason, and P. Ponka, “The long history of iron in the Universe and in health and disease,” Biochimica et Biophysica Acta, vol. 1820, no. 3, pp. 161–187, 2012. View at Publisher · View at Google Scholar · View at Scopus
  9. D. J. Weatherall and J. B. Clegg, The Thalassemia Syndromes, Blackwell Scientific Publications, Oxford, UK, 3rd edition, 1981.
  10. C. Chaisue, S. Kitcharoen, P. Wilairat, A. Jetsrisuparb, G. Fucharoen, and S. Fucharoen, “α/β-Globin mRNA ratio determination by multiplex quantitative real-time reverse transcription-polymerase chain reaction as an indicator of globin gene function,” Clinical Biochemistry, vol. 40, no. 18, pp. 1373–1377, 2007. View at Publisher · View at Google Scholar · View at Scopus
  11. K. J. Livak and T. D. Schmittgen, “Analysis of relative gene expression data using real-time quantitative PCR and the 2-CT method,” Methods, vol. 25, no. 4, pp. 402–408, 2001. View at Publisher · View at Google Scholar · View at Scopus
  12. J. L. Vaerman, P. Saussoy, and I. Ingargiola, “Evaluation of real-time PCR data,” Journal of Biological Regulators & Homeostatic Agents, vol. 18, no. 2, pp. 212–214, 2004. View at Google Scholar · View at Scopus
  13. J. Ross, “Messenger RNA turnover in cell-free extracts from higher eukaryotes,” Methods in Molecular Biology, vol. 118, pp. 459–476, 1999. View at Google Scholar · View at Scopus
  14. A. Krowczynska and G. Brawerman, “Structural features in the 3′-terminal region of polyribosome-bound rabbit globin messenger RNAs,” Journal of Biological Chemistry, vol. 261, no. 1, pp. 397–402, 1986. View at Google Scholar · View at Scopus
  15. M. S. Gündogdu, H. Liu, D. Metzdorf et al., “The haematopoietic GTPase RhoH modulates IL3 signalling through regulation of STAT activity and IL3 receptor expression,” Molecular Cancer, vol. 9, article 225, 2010. View at Publisher · View at Google Scholar · View at Scopus
  16. R. M. Böhmer, “Erythropoiesis from adult but not fetal blood-derived CD133+ stem cells depends strongly on interleukin-3,” Growth Factors, vol. 22, no. 1, pp. 45–50, 2004. View at Publisher · View at Google Scholar · View at Scopus