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Anemia
Volume 2017, Article ID 3106890, 7 pages
https://doi.org/10.1155/2017/3106890
Research Article

Efficacy and Tolerability of Intravenous Ferric Carboxymaltose in Patients with Iron Deficiency at a Hospital Outpatient Clinic: A Retrospective Cohort Study of Real-World Clinical Practice

1Hospital de Dia de Imuno-Hemoterapia, Hospital Pulido Valente, Centro Hospitalar Lisboa Norte (CHLN), Alameda das Linhas de Torres 117, 1769-001 Lisboa, Portugal
2Hospital de Dia de Imuno-Hemoterapia, Hospital de Santa Maria, CHLN, Avenida Prof. Egas Moniz, 1649-035 Lisboa, Portugal

Correspondence should be addressed to António Robalo Nunes; moc.liamg@senunolabor

Received 17 March 2017; Revised 29 May 2017; Accepted 1 June 2017; Published 3 July 2017

Academic Editor: Ajit C. Gorakshakar

Copyright © 2017 António Robalo Nunes et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. E. McLean, M. Cogswell, I. Egli, D. Wojdyla, and B. De Benoist, “Worldwide prevalence of anaemia, WHO Vitamin and Mineral Nutrition Information System, 1993–2005,” Public Health Nutrition, vol. 12, no. 4, pp. 444–454, 2009. View at Publisher · View at Google Scholar · View at Scopus
  2. World Health Organization, Iron Deficiency Anaemia: Assessment, Prevention and Control. A Guide for Programme Managers, World Health Organization, Geneva, Switzerland, 2001.
  3. C. Fonseca, F. Marques, A. Robalo Nunes, A. Belo, D. Brilhante, and J. Cortez, “Prevalence of anaemia and iron deficiency in Portugal: the EMPIRE study,” Internal Medicine Journal, vol. 46, no. 4, pp. 470–478, 2016. View at Publisher · View at Google Scholar · View at Scopus
  4. C. Rognoni, S. Venturini, M. Meregaglia, M. Marmifero, and R. Tarricone, “Efficacy and Safety of Ferric Carboxymaltose and Other Formulations in Iron-Deficient Patients: A Systematic Review and Network Meta-analysis of Randomised Controlled Trials,” Clinical Drug Investigation, vol. 36, no. 3, pp. 177–194, 2016. View at Publisher · View at Google Scholar · View at Scopus
  5. J. E. Toblli and M. Angerosa, “Optimizing iron delivery in the management of anemia: patient considerations and the role of ferric carboxymaltose,” Drug Design, Development and Therapy, vol. 8, pp. 2475–2491, 2014. View at Publisher · View at Google Scholar · View at Scopus
  6. G. R. Bailie, N. A. Mason, and T. G. Valaoras, “Safety and tolerability of intravenous ferric carboxymaltose in patients with iron deficiency anemia,” Hemodialysis International, vol. 14, no. 1, pp. 47–54, 2010. View at Publisher · View at Google Scholar · View at Scopus
  7. G. C, “Doron Schwartz, Should a search for iron deficiency be part of the regular screening in all patients, whether anemic or not?” Journal of Hematology & Thromboembolic Diseases, vol. 02, no. 05, 2014. View at Google Scholar
  8. G. M. Keating, “Ferric carboxymaltose: a review of its use in iron deficiency,” Drugs, vol. 75, no. 1, pp. 101–127, 2015. View at Publisher · View at Google Scholar · View at Scopus
  9. K. A. Lyseng-Williamson and G. M. Keating, “Ferric carboxymaltose: a review of its use in iron-deficiency anaemia,” Drugs, vol. 69, no. 6, pp. 739–756, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. G. R. Bailie, “Efficacy and safety of ferric carboxymaltose in correcting iron-deficiency anemia: a review of randomized controlled trials across different indications.,” Arzneimittel-Forschung, vol. 60, no. 6 a, pp. 386–398, 2010. View at Google Scholar · View at Scopus
  11. J. E. Onken, D. B. Bregman, R. A. Harrington et al., “A multicenter, randomized, active-controlled study to investigate the efficacy and safety of intravenous ferric carboxymaltose in patients with iron deficiency anemia,” Transfusion, vol. 54, no. 2, pp. 306–315, 2014. View at Publisher · View at Google Scholar · View at Scopus
  12. R. A. Moore, H. Gaskell, P. Rose, and J. Allan, “Meta-analysis of efficacy and safety of intravenous ferric carboxymaltose (Ferinject) from clinical trial reports and published trial data,” BMC Blood Disorders, vol. 11, article 4, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. M. Kuster and D. N. Meli, “Treatment of iron deficiency with intravenous ferric carboxymaltose in general practice: a retrospective database study,” Journal of Clinical Medicine Research, vol. 7, no. 1, pp. 37–40, 2015. View at Publisher · View at Google Scholar
  14. M. Varcher, S. Zisimopoulou, O. Braillard, B. Favrat, and N. J. Perron, “Iron deficiency intravenous substitution in a Swiss academic primary care division: Analysis of practices,” International Journal of General Medicine, vol. 9, pp. 221–227, 2016. View at Publisher · View at Google Scholar · View at Scopus
  15. L. Peyrin-Biroulet, N. Williet, and P. Cacoub, “Guidelines on the diagnosis and treatment of iron deficiency across indications: A systematic review,” American Journal of Clinical Nutrition, vol. 102, no. 6, pp. 1585–1594, 2015. View at Publisher · View at Google Scholar · View at Scopus
  16. A. M. Ganzoni, “Intravenous iron-dextran: therapeutic and experimental possibilities,” Schweizerische Medizinische Wochenschrift, vol. 100, no. 7, pp. 301–303, 1970. View at Google Scholar · View at Scopus
  17. World Health Organization, International statistical classification of diseases and related health problems. - 10th revision, World Health Organization, Geneva, Switzerland, 2016.
  18. R. Mahey, A. Kriplani, K. D. Mogili, N. Bhatla, G. Kachhawa, and R. Saxena, “Randomized controlled trial comparing ferric carboxymaltose and iron sucrose for treatment of iron deficiency anemia due to abnormal uterine bleeding,” International Journal of Gynecology and Obstetrics, vol. 133, no. 1, pp. 43–48, 2016. View at Publisher · View at Google Scholar · View at Scopus
  19. S. Garcia-Lopez, J. M. Bocos, J. P. Gisbert et al., “High-dose intravenous treatment in iron deficiency anaemia in inflammatory bowel disease: early efficacy and impact on quality of life,” Blood Transfusion = Trasfusione del Sangue, vol. 14, no. 2, pp. 199–205, 2016. View at Google Scholar
  20. M. Bach, T. Geisel, J. Martin et al., “Efficacy and Safety of Intravenous Ferric Carboxymaltose in Geriatric Inpatients at a German Tertiary University Teaching Hospital: A Retrospective Observational Cohort Study of Clinical Practice,” Anemia, vol. 2015, Article ID 647930, 2015. View at Publisher · View at Google Scholar · View at Scopus
  21. R. Herfs, L. Fleitmann, and I. Kocsis, “Treatment of iron deficiency with or without anaemia with intravenous ferric carboxymaltose in gynaecological practices—a non-interventional study,” Geburtshilfe und Frauenheilkunde, vol. 74, no. 1, pp. 81–88, 2014. View at Publisher · View at Google Scholar · View at Scopus
  22. T. A. Koch, J. Myers, and L. T. Goodnough, “Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations,” Anemia, vol. 2015, Article ID 763576, 2015. View at Publisher · View at Google Scholar · View at Scopus
  23. B. Favrat, K. Balck, C. Breymann et al., “Evaluation of a single dose of ferric carboxymaltose in fatigued, iron-deficient women—PREFER a randomized, placebo-controlled study,” PLoS ONE, vol. 9, no. 4, Article ID e94217, 2014. View at Publisher · View at Google Scholar · View at Scopus
  24. C. F. Barish, T. Koch, A. Butcher, D. Morris, and D. B. Bregman, “Safety and efficacy of intravenous ferric carboxymaltose (750 mg) in the treatment of iron deficiency anemia: two randomized, controlled trials,” Anemia, vol. 2012, Article ID 172104, 9 pages, 2012. View at Publisher · View at Google Scholar · View at Scopus
  25. P. Geisser and J. Banké-Bochita, “Pharmacokinetics, safety and tolerability of intravenous ferric carboxymaltose: a dose-escalation study in volunteers with mild iron-deficiency anaemia,” Arzneimittel-Forschung, vol. 60, no. 6a, pp. 362–372, 2010. View at Google Scholar · View at Scopus