Anemia

Anemia / 2019 / Article / Tab 1

Research Article

A Comparative Study of Interleukin 6, Inflammatory Markers, Ferritin, and Hematological Profile in Rheumatoid Arthritis Patients with Anemia of Chronic Disease and Iron Deficiency Anemia

Table 1

Demographic, hematological, and immunological parameters comparison between healthy control and RA patients and between anemic and nonanemic RA patients.

Comparison betweenHealthy control and total RA patientsanemic RA and nonanemic RA patients

GroupsHealthy controlTotal RA patientsP≤ anemic RAnon- anemic RAP<
ParameterN=50N=59N=43N=16
Sex, F/M46/ 451/ 8NS36/7(72.8)15/1(27.2%)0.001
Female%92%86.40%83.70%93.70%
Male, %8%13.60%16.30%6.25%
Age (years)38.78±7.4738.44±11.43NS40.23±10.7433.6±12.20.02
(25-55)(21-60)(24-60)(21-58)
WBC(/μ)L5.5±2.67.39±1.70.016.62±0.4125.20±0.619NS
RBC(/μL)4.88±0.463.99±0.910.0013.83±1.014.427±0.3300.005
HGB (g/dl)13.2±1.2810.27±1.80.019.45±1.3012.46±0.980.005
MCV(fl)87.64± 5.782.8±7.640.0581.62±8.3886.06±3.690.006
MCH (pg)27.12±2.4326.83±4.09NS26.25±4.528.39±1.4NS
MCHC(g/L)31.87±1.1732.01±3.520.0231.65±4.0132.99±1.30NS
ESR (mm/h)7.98±3.7659.77±4.340.00168.34±33.536.75±19.60.002
hsCRP (mg/L)0.96±0.807.480±2.50.0017.1±2.48.4 ± 2.50.03
Anti-CCP (U/ml)2.4±1.46325.5±34.70.001289.2±37.4423.1±75.90.01
IL-6 (pg/mL)4.94±.342483.32±35.40.0001444.2±39.6588.39±71.50.02
ferritin (ng/mL) 56.5 ±5.4783.3±3.240.00197.93±21.533.6±5.070.01

P is statistically significant at level < 0.05.
Data are reported as mean ± standard deviation (range).
WBC: white blood cells; RBC: red blood cells; HGB: hemoglobin; HCT: haematocrit; MCV: mean corpuscular volume, MCH: mean corpuscular hemoglobin; MCHC: mean corpuscular hemoglobin concentration; ESR: erythrocyte sedimentation rate; hsCRP: high sensitivity C-reactive protein, IL-6: interleukin 6, anti-CCP: anti-cyclic citrullinated peptide; NS: not significant; F: female; M: male.