Research Article
Correlations between Iron Load and CD4 in Adult Transfusion-Dependent Beta Thalassemia
Table 1
Baseline characteristics of study subjects.
| | Variables | Gender | N = 64 | | Male (n = 31 [48.4%]) | Female (n = 33 [51.6%]) |
| | Age (years) | | Median (range) | 22 (18, 37) | 21 (19, 33) | 22 (18, 37) |
| | Type of thalassemia | | Thalassemia β major | 14 (45.2) | 13 (39.4) | 27 (42.2) | | Thalassemia β HbE | 17 (54.8) | 20 (60.6) | 37 (57.8) |
| | Chronic infectious diseases | | HIV | 0 | 0 | 0 | | Hepatitis B | 0 | 1 (3.0) | 1 (1.6) | | Hepatitis C | 5 (16.1) | 0 | 5 (7.8) | | Hepatitis B and C | 0 | 2 (6.1) | 2 (3.1) | | TBC (N = 41) | 2 (6.5) | 2 (6.1) | 4 (9.8) |
| | First transfusion | | Less than 6 years | 24 (77.4) | 26 (78.8) | 50 (78.1) | | More than 6 years | 7 (22.6) | 7 (21.2) | 14 (21.9) |
| | Number of transfusions | | More than 1 time per month | 21 (67.7) | 24 (72.7) | 45 (70.3) | | One month | 10 (32.3) | 9 (27.3) | 19 (29.7) |
| | Iron-chelating drug | | Mono | 26 (83.9) | 30 (90.9) | 56 (87.5) | | Combination | 5 (16.1) | 3 (9.1) | 8 (12.5) |
| | Regularity of taking medicine | | Not a routine | 24 (77.4) | 26 (78.8) | 50 (78.1) | | Routine | 7 (22.6) | 7 (21.2) | 14 (21.9) |
| | Enlargement of the spleen (splenomegaly) | | Normal | 4 (12.9) | 3 (9.1) | 7 (10.9) | | Splenomegaly | 27 (87.1) | 30 (90.9) | 57 (89.1) |
| | Facies Cooley | | No | 16 (51.6) | 18 (54.5) | 34 (53.1) | | Yes | 15 (48.4) | 15 (45.5) | 30 (46.9) |
| | Hemoglobin (g/dL)∗ | 8.2 (1.3) | 7.8 (1.1) | 8.01 (1.2) | | The mean (SB) |
| | Leukocyte (10^3/uL) | 4.9 (2.3, 9.5) | 4.7 (1.7, 11.6) | 4.9 (1.7, 11.6) | | Median (range) |
| | Neutrophils | 2820 (920, 5460) | 2770 (730, 7160) | 2795 (730, 7160) | | Median (range) |
| | Platelets (10^3/uL) | 135 (41, 331) | 130 (52, 366) | 131 (41, 366) | | Median (range) |
| | Hs CRP (mg/L) | 2.0 (0.4, 9.5) | 1.6 (0.6, 8.9) | 1.8 (0.4, 9.5) | | Median (range) |
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