Proximal Femoral Allograft for Major Segmental Femoral Bone Loss: A Systematic Literature Review

Table 4

Table showing complications of prosthesis into allograft to form the allograft prosthesis composite (APC) and methods for securing APC to distal host femur. The total cohort included 498 patients with a mean follow up of 8.1 years (range 2 to 16.2 years). The pooled success rate was 81% (95% CI 77%–86%). Success rate: APC not revised. NR: not reported. Study numbers correlate with Table 1.

Study	𝑛	Failed constructs	Success rate	Infection	Dislocation	Aseptic loosening or fracture
1	30	3	90%	1 (3.3%)	5 (16.7%)	4 (13.3%)
2	21	2	82%	0	0	6 (28.6%)
3	55	6	85%	2 (3.6%)	4 (7.3%)	5 (9.1%)
4	14	4	78%	3 (21.4%)	NR	1 (7.1%)
5	15	3	73%	1 (6.7%)	6 (40%)	2 (13.3%)
6	50	8	84%	2 (4%)	4 (8%)	7 (14.0%)
7	44	4	91%	1 (2.3%)	6 (13.6%)	3 (6.8%)
8	72	19	66%	5 (6.9%)	8 (11.1)	14 Loosening (4), resorption (3), nonunion (2), fracture (4), stem fracture (1)
9	15	2	87%	1 (6.7%)	1 (6.7%)	1 (6.7%)
10	73	13	82%	8 (10.9%)	0	11 (15.1%)
11	32	9	72%	4 (12.5%)	NR	5 (15.6%)
12	22	2	91%	1 (4.5%)	NR	1 (4.6%)
13	20	1	95%	1 (5.0%)	2 (10%)	0
14	25	2	92%	1 (4.0%)	NR	2 (8.0%)
15	37	10	73%	3 (8.1%)	NR	7 (18.9%)
16	15	5	67%	3 (20%)	1 (6.7)	4 (20.7%)