Predicting Fracture Risk in Patients with Metastatic Bone Disease of the Femur: A Pictorial Review Using Three Different Techniques

Figure 8

True negative (CTRA-/Fx-) (Case 7, L femur). (a) This is a 72-year-old female with breast cancer and extensive MBD showing a mixed osteoblastic and osteolytic lesion in the left femoral diaphysis. (b) While CTRA predicted that the subject would not fracture, FEA did predict fracture. (c) She was followed for two years without evidence of fracture. Imaging taken at 20 months demonstrates MBD without a fracture.

(a)

(b)

(c)