Table of Contents
Advances in Orthopedic Surgery
Volume 2014, Article ID 495426, 4 pages
Clinical Study

Incidence of Heterotopic Ossification in Patients Receiving Radiation Therapy following Total Hip Arthroplasty

1Orthopaedic Clinic, Attikon Hospital, University of Athens, Olympic Village Polyclinic, 36122 Athens, Greece
2New York Hospital, Cornell University, NY 10021, USA
3Hospital for Special Surgery, Cornell University, NY 10021, USA

Received 20 October 2013; Revised 29 January 2014; Accepted 14 February 2014; Published 27 April 2014

Academic Editor: Guoxin Ni

Copyright © 2014 Panagiotis Koulouvaris et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Heterotopic ossification (HO) is a frequent complication of hip surgery. In this study the incidence of HO is analyzed in high risk patients who received radiation therapy (RT) after total hip replacement (THA) with regular and miniposterolateral hip approach. Two hundred and thirty five high risk patients received a single dose of 700 rad after THA. The incidence of HO was 15.7%. The incidence of HO in the high risk subgroup with the miniincision was lower (5.7%) but not significantly different ( ). Hypertrophic osteoarthritis was demonstrated to be the consistent predisposing factor for HO formation ( ).