A New 3D Simulation Method for the Construction of Optical Phase Contrast Images of Gold Nanoparticle Clusters in Biological Cells

Figure 6

OPCM images of a biological cell for different values (a: −150^∘, b: −90^∘, c: 90^∘, d: 180^∘) of the phase offset between the reference and diffracted beam of the OPCM at optical immersion conditions (left) including a cluster of 42 gold NPs (middle: no resonance, right: at resonance) located in a position symmetrically opposite to the nucleus. The arrows indicate the position of the gold NP cluster.

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