Prophylactic Effects of Ethanolic Extract of Irvingia gabonensis Stem Bark against Cadmium-Induced Toxicity in Albino Rats

Table 5

Changes in the activities of serum, hepatic, and cardiac alanine and aspartate aminotransferases in cadmium-induced rats treated with ethanolic extract of Irvingia gabonensis.

Treatments	Liver (U/L)		Heart (U/L)		Serum (U/L)
	AST	ALT	AST	ALT	AST	ALT
Control	57.80 ± 3.42	48.45 ± 2.29	48.45 ± 0.02	55.56 ± 2.24	4.54 ± 1.77	6.37 ± 1.46
Cadmium untreated	28.74 ± 2.62*	22.48 ± 2.26*	26.22 ± 2.38*	23.24 ± 4.04*	8.39 ± 0.56*	9.89 ± 2.24*
Cadmium + 200 mg/kg	42.56 ± 1.88**	38.10 ± 1.12**	39.02 ± 1.25**	39.12 ± 1.24**	4.13 ± 1.50**	5.78 ± 1.38**
Cadmium + 400 mg/kg	51.32 ± 0.34**	44.01 ± 1.05**	42.02 ± 1.45**	47.12 ± 1.02**	4.01 ± 1.42**	6.01 ± 1.28**

Values are means ± s.e.m. of 5 animals per group; cadmium untreated = at 50 mg/kg; cadmium treated = Irvingia gabonensis at 200 mg/kg; cadmium treated = Irvingia gabonensis at 400 mg/kg; *significantly different from control (); **significantly different from cadmium untreated ().