Advances in Pharmaceutics / 2015 / Article / Tab 2

Research Article

Enhanced Degradation of Lactide-co-Glycolide Polymer with Basic Nucleophilic Drugs

Table 2

Rate constant and half-life for Placebo, Olanzapine, and Risperidone microspheres.

% drug loading
Parameter measured015101535
PlaceboRisp.Olanz.Risp.Olanz.Risp.Olanz.Risp.Olanz.Risp.

or (day−1)0.0030.1480.0470.1410.0770.1840.0830.3590.0800.306
or (day)2134.6814.64.918.973.778.351.938.632.267
(day−1)0.0070.0140.0140.0600.053
(day)102.348.149.511.513.2