QSAR Study of (5-Nitroheteroaryl-1,3,4-Thiadiazole-2-yl) Piperazinyl Derivatives to Predict New Similar Compounds as Antileishmanial Agents

Table 1

Chemical structures of thiadiazole derivatives used in this study.

N°	Het	Ar	pIC50	N°	Het	Ar	pIC50
1	Het1		4.932	19	Het3		4.592
2	Het1		4.969	20	Het3		5.029
	Het1		4.880	21	Het3		4.797
	Het1		4.581	22	Het1		3.983
5	Het1		4.717	23	Het1		3.955
6	Het1		4.921	24	Het1		4.638
7	Het1		4.882	25	Het1		4.482
8	Het2		4.602	26	Het1		5.000
9	Het2		4.463	27	Het1		4.959
	Het2		4.222	28	Het1		4.482
	Het2		4.618	29	Het1		5.046
12	Het2		4.549	30	Het1		4.097
13	Het2		4.880	31	Het1		4.022
14	Het2		4.581	32	Het1		4.032
15	Het3		4.983	33	Het1		3.155
16	Het3		4.693	34	Het1		3.222
	Het3		4.748	35	Het1		4.143
	Het3		4.367	36	Het1		4.319

set.