Research Article

Comparison of General Practice and Pharmaceutical Dispensing Data for Pharmacoepidemiological Research: Assessing the Risk of Urinary-Tract Infections with Sodium Glucose Cotransporter 2 Inhibitors for Diabetes

Table 2

Other indicators.

MedicineInsight 10 PBS
SGLT2 cohort (N=1977)SGLT2 cohort (N=3120)

Type of the index medicineDapagliflozin – 93Dapagliflozin – 87
Canagliflozin – 3Canagliflozin – 9
Empagliflozin – 4Empagliflozin – 4

Strength at initiationDapagliflozin initiators – all on 10mg (one strength)Dapagliflozin initiators – all on 10mg (one strength)
Canagliflozin initiators – 78 on 300mg (higher strength)Canagliflozin initiators – 77 on 300mg (higher strength)
Empagliflozin initiators – 74 on 10mg (lower strength) Empagliflozin initiators – 72 on 10mg (lower strength)

Prior diabetes therapy  
(prior 12 months)
90 had documented diabetes medicine80 had dispensing for diabetes medicine
86 had metformin and/or sulfonylurea69 had metformin and/or sulfonylurea

Interacting medicines  
(3 months prior and 6 months post index)
ACE/ARB – 61ACE/ARB – 61
NSAIDs – 14NSAIDs – 14
Frusemide – 6Frusemide – 7