Research Article

Comparison of General Practice and Pharmaceutical Dispensing Data for Pharmacoepidemiological Research: Assessing the Risk of Urinary-Tract Infections with Sodium Glucose Cotransporter 2 Inhibitors for Diabetes

Table 4

Risk of UTIs.

ā€‰MedicineInsight data10 PBS data

ā€‰Unadjusted Hazard ratio (HR),Adjusted Hazard ratio (aHR),Unadjusted Hazard ratio (HR),Adjusted Hazard ratio (aHR),
95% CI95% CI95% CI95% CI

SGLT2 vs DPP-4 cohort0.88 (0.65-1.19)0.90 (0.66-1.24)0.75 (0.60-0.94)0.90 (0.72-1.13)

Note: In the 10 PBS data the adjusted hazard ratio (aHR) is adjusted for prior infection, age, gender, and comorbidity; in the MedicineInsight data the adjusted hazard ratio (aHR) is adjusted for prior infection, age, gender, weight, HbA1c, location, smoking status, and comorbidity.