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Advances in Pharmacological and Pharmaceutical Sciences

Advances in Pharmacological and Pharmaceutical Sciences / 2010 / Article / Tab 1

Research Article

The Role of Tetrahydrobiopterin and Dihydrobiopterin in Ischemia/Reperfusion Injury When Given at Reperfusion

Table 1

The effects of BH4 or BH2 on NO release from nonischemic rat aortic segments.
Basal/TreatmentsNO release
(picomoles/mg tissue)		Sample No.
Basal2.28 0.25
Ach (5  M)
BH4 (1  M)2.74 0.16
BH4 (10  M)4.45 0.43*
BH4 (20  M)
BH4 (40  M)
BH2 (50  M)
BH2 (100  M)
BH2 (200  M)
Ach (5  M)+L-NAME (800  M)
BH4 (10  M)+L-NAME (800  M)
BH2 (100  M)+L-NAME (800  M)
compared to basal NO release; compared to the effects of BH4 on NO release.

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