Chronic Treatment with a Promnesiant GABA-A 𝜶𝟓-Selective Inverse Agonist Increases Immediate Early Genes Expression during Memory Processing in Mice and Rectifies Their Expression Levels in a Down Syndrome Mouse Model

Figure 5

PCA on IEGs expression measured on microarrays. The first principal component fully discriminated euploid and Ts65Dn mice. The second principal component partially discriminated vehicle- and α5IA-treated mice.