Differential Neuroprotection of Selective Estrogen Receptor Agonists against Autonomic Dysfunction and Ischemic Cell Death in
Permanent versus Reperfusion Injury
Figure 2
Effect of pretreatment with either 7.5% DMSO or DPN (i.v.; 30 minutes) on infarct volume (mm3) calculated from TTC-stained 1 mm thick coronal sections throughout the extent of the infarct following I/R (a) and MCAO (b). Each bar represents the mean ± S.E.M ( = 4–6/group), and *indicates significance () from the DMSO control group. (c) Representative photomicrographs of TTC stained, 1 mm thick coronal slices illustrating the extent of the infarct within the prefrontal cortex following 30 minutes pretreatment (i.v.) with either DMSO or DPN (1 mg/kg) at 6 hours post-I/R.
