Analgesic and Anti-Inflammatory Activity of Pinus roxburghii Sarg.

Table 1

Protective efeect of Pinus roxburghii Sarg. on paw edema induced by carrageenan in rat.

		Change in paw volume (mL) Mean ± SEM
Groups	Drug (dose), route	Time (hr)
		1 hr	2 hr	3 hr	4 hr
Control	Tween 80 (5%) p.o	0.71±0.12	0.93±0.01	1.8±0.03	1.9±0.02
Standard	Indomethacin (10 mg/kg), p.o	0.21±0.06(70.4)	0.23±0.02^∗∗(75.26)	0.41±0.01^∗∗(77.22)	0.35±0.09(81.56)
AB	100 mg/kg, p.o	0.61±0.17(14.08)	0.92±0.17(1.07)	0.89±0.13^∗∗(50.55)	1.07±0.19(43.68)
AB	300 mg/kg, p.o	0.63±0.14(11.21)	0.78±0.19(16.12)	0.79±0.20^∗∗(56.11)	1.87±0.14(1.57)
AB	500 mg/kg, p.o	0.39±0.12(45.07)	0.52±0.13(44.08)	0.68±0.11^∗∗(62.22)	0.68±0.11(64.21)

𝑛=5. Results are expressed as mean ± SEM. Percentage inhibition are in brackets.
^∗𝑃>0.05, ^∗∗𝑃<0.01 as compared to control, AB = alcoholic bark extract.