Advances in Pharmacological and Pharmaceutical Sciences / 2012 / Article / Fig 12

Research Article

Allosteric Modulation of Beta1 Integrin Function Induces Lung Tissue Repair

Figure 12

Selected frames from time lapse videos of epithelial-mesenchymal cultures during stretch (compressed videos) demonstrating the formation of F-actin (blue) and caspase 3/7 activation (red) in reponse to elastase (PPE, 0.6 U/mL) and its inhibition by JB1a done on cells cultured on glass. Sytox green was used for cell tracking. (a) control, (b) PPE (0.6 U/mL), and (c) PPE + JB1a (1 ug/mL).