Effect of Coenzyme-Q10 on Doxorubicin-Induced Nephrotoxicity in Rats
Figure 4
Effect of two doses of coenzyme Q10 (CoQ10) on renal caspase 3 immunohistochemical semiquantitative analysis in rats exposed to doxorubicin- (Dox-) induced nephrotoxicity. Kidneys were isolated from control untreated group, animals treated with low or high dose CoQ10 (CoQ10L or CoQ10H, resp.), and animals treated with Dox, or with Dox together with CoQ10L or CoQ10H, respectively. Values are represented as means ± SE of number of immuno-positive cells for caspase 3 in sections of 3 animals of each group, 5 fields/section. Significant difference compared with control and significant difference compared to Dox, with significant difference from control. Significant difference is reported when .
