Curcumin Ameliorates Methotrexate-Induced Nephrotoxicity in Rats

<table>Effect of curcumin (Curc) on renal malondialdehyde (a), nitric oxide (as nitrite/nitrate; (b)), glutathione peroxidase (c), and superoxide dismutase (d) levels of methotrexate- (Meth-) induced nephrotoxicity in rats. Data are mean ± SEM of 6–8 rats. <svg height="16.75" id="M5" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 22.475 16.75" width="22.475" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>Significantly different from control, Curc, and Meth groups, respectively, at <svg height="11.375" id="M6" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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Advances in Pharmacological and Pharmaceutical Sciences

Curcumin Ameliorates Methotrexate-Induced Nephrotoxicity in Rats

Figure 3