Advances in Pharmacological and Pharmaceutical Sciences / 2013 / Article / Tab 2

Review Article

Phytochemistry, Pharmacology and Toxicology of Spilanthes acmella: A Review

Table 2

Summary of pharmacological actions of Spilanthes acmella.

SL. no.Pharmacological activityParts of plant usedExperimental modelsAnimals usedReferences

1Local anaesthetic Whole plantIntracutaneous wheal in guinea pigs and plexus anaesthesia in frogGuinea pig, frog[19]
2Antipyretic activityWhole plantYeast induced pyrexiaAlbino rats[19]
3Anti-inflammatory activityWhole plant, leavesCarrageenan induced paw oedemaAlbino rats[22, 31]
4Analgesic activityWhole plantTail flick method,
acetic acid induced abdominal constriction
Albino rats[22]
5Antifungal activityFlowers[23]
6Diuretic activityFlowers (cold water extract), whole plantInduction of dieresis using cold water extractAlbino rats[24, 25]
7Vasorelaxant activityFlowersPartially endothelium induced nitric oxide and PGI2Albino rats[30, 31]
8Antioxidant activityLeaves & whole plantDPPH Assay, TBARs and SOD methodInvitro, no animal[30, 31]
9Pancreatic lipase inhibitionFlowersInvitro, no animal[29]
10Antimalarial & larvicidal activitySpilanthol extracted from whole plantEggs & pupae of vector[37]
11Aphrodisiac activityWhole plantMale rats[1]
12Antinociceptive activityWhole plantAcetic acid induced writhing Mice[31]
13Immunomodulatory activityWhole plantRats[36]
14BioinsecticidalWhole plant, leaves[2, 12, 32]
15ConvulsantWhole plantElectroencephalogram (EEG) analysisAlbino rat[25]

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