Antioxidant Potential of a Polyherbal Antimalarial as an Indicator of Its Therapeutic Value

Table 3

Effect of Nefang on biochemical parameters in CCl₄-treated Wistar rats.

Biochemical parameters	Group A; (corn oil)	Group B; ( CCl4)	Group C; (CCl4 + 100 mg/kg Nefang)	Group D; (CCl4 + 500 mg/kg Nefang)
GLU (mg/dL)	124.07 ± 5.69	151.87 ± 5.03*	160.04 ± 4.31	154.30 ± 10.69
CHOL (mg/dL)	86.98 ± 7.60	74.92 ± 7.69*	135.71 ± 23.80^##	91.42 ± 5.03
TGY (mg/dL)	227.47 ± 5.89	142.28 ± 25.27**	154.89 ± 18.60^#	166.01 ± 3.35^#
ALT (UI/L)	16.97 ± 2.05	97.38 ± 5.26**	126.67 ± 12.08^##	54.78 ± 2.85^##
AST (UI/L)	35.52 ± 3.94	69.52 ± 1.29**	63.77 ± 7.01^#	54.84 ± 7.75^#
BUN (mg/dL)	35.63 ± 3.01	40.73 ± 1.50*	39.08 ± 3.32	33.12 ± 0.38^#
CRE (mg/dL)	0.77 ± 0.09	0.88 ± 0.83*	0.88 ± 0.04	0.76 ± 0.05^#

GLU: glucose, CHOL: cholesterol, TGY: triglycerides, ALT: alanine aminotransferase, AST: aspartate aminotransferase, BUN: blood urea nitrogen, CRE: creatinine. results presented as mean ± SD; 𝑛=5; significant difference: compared to normal control—*𝑃<0.05, **𝑃<0.01, compared to untreated control— ^#𝑃<0.05, ^##𝑃<0.01.