Effects of Melatonin and Epiphyseal Proteins on Fluoride-Induced Adverse Changes in Antioxidant Status of Heart, Liver, and Kidney of Rats

Table 4

Effect of different treatments on lipid peroxidation (LPO), catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx), glutathione reductase (GR), and reduced glutathione (GSH) in kidney of female rats (𝑛=6; means ± S.E.).

Group	Parameter
	LPO; (nM MDA/mL)	CAT; (nM/min/mg protein)	SOD (U)*	GR; (nM/min/mg protein)	GPx; (nM/min/mg protein)	GSH; (μM/g tissue)
Control	4.99^a±0.130	251.70^a±4.58	5.98^b±0.17	126.64^c±8.47	20.13^b±1.11	3.50^b±0.06
F	16.62^c±0.360	382.46^c±14.89	2.56^a±0.12	41.11^a±5.40	14.38^a±0.49	2.68^a±0.09
F + BEP	6.90^b±0.140	295.11^b±4.22	5.64^b±0.37	85.85^b±3.97	20.18^b±2.59	3.76^b±0.08
F + MEL	6.88^b±0.089	307.06^b±5.24	5.96^b±0.28	93.01^b±7.78	18.43^b±0.83	3.25^b±0.10

Comparisons are between the rows. Values in the same column bearing no common superscripts (a, b, and c) differ significantly (𝑃<0.05).
*The activity was expressed as U/g of protein [one unit of SOD is the amount (Δg) of protein required to inhibit the MTT reduction by 50%].