Effects of Methanol Extract of Breadfruit (Artocarpus altilis) on Atherogenic Indices and Redox Status of Cellular System of Hypercholesterolemic Male Rats

Table 1

Changes in the body weight and relative weight of organs of hypercholesterolemic rats treated with methanol extract of Artocarpus  altilis for nine weeks.

Treatment	Body weight (g)		Weight of organs (g)			Relative weight of organs
	Initial	Final	Liver	Kidney	Heart	Liver	Kidney	Heart
Control	151.00±4.94	194.00±23.02	5.38±0.49	1.03±0.11	0.53±0.09	2.77±0.75	0.53±0.05	0.27±0.04
HC	160.00±3.10	198.00±29.03	6.89±0.89	1.09±0.14	0.69±0.06	3.48±0.23^∗	0.55±0.03	0.39±0.02^∗
HC + AA1	159.00±5.48	196.00±37.15	5.12±1.22	1.09±0.20	0.55±0.08	2.61±0.13^∗∗	0.56±0.04	0.28±0.03^∗∗
HC + AA2	167.00±6.04	185.00±45.00	5.20±1.24	1.09±0.20	0.52±0.09	2.81±0.15^∗∗	0.59±0.06	0.28±0.04^∗∗
HC + QUE	173.00±4.74	202.50±5.00	5.39±1.05	1.19±0.07	0.55±0.01	2.66±0.43^∗∗	0.59±0.05	0.27±0.01^∗∗
QUE	188.00±3.95	225.00±20.41	5.06±1.21	1.17±0.05	0.51±0.49	2.24±0.41	0.52±0.07	0.23±0.04
AA2	192.00±8.34	235.00±22.36	5.19±0.55	1.21±0.11	0.62±0.06	2.21±0.17	0.52±0.04	0.26±0.03

Values are means ± SD of 5 animals per group; HC: cholesterol at 30 mg/0.3 mL.
AA1: Artocarpus  altilis at 100 mg/kg, AA2: Artocarpus  altilis at 200 mg/kg, and QUE: Questran at 0.26 g/kg.
*Significantly different from control (𝑃<0.05), **significantly different from HC (𝑃<0.05).