Comparative Evaluation of Cytotoxic and Apoptogenic Effects of Several Coumarins on Human Cancer Cell Lines: Osthole Induces Apoptosis in p53-Deficient H1299 Cells
Involvement of activation of caspases in the induction of apoptosis on (a) SKNMC, (b) PC3, and (c) H1299 human cancer cells. Cells were incubated with concentration of the indicated compounds and harvested at 24 h and cell lysates were assayed using microplate reader for activation caspases. Significant differences were compared with the control. Data are presented as mean ± S.E.M. , , and versus control.