Enzyme Inhibitory Properties, Antioxidant Activities, and Phytochemical Profile of Three Medicinal Plants from Turkey

Table 3

Inhibition concentration of the plant extracts on cholinesterases, tyrosinase, α-amylase, and α-glucosidase.

Plant extracts/positive controls	IC50 (mg/mL)
	Cholinesterases		Tyrosinase	α-Amylase	α-Glucosidase
	Acetylcholinesterase	Butyrylcholinesterase
HvEA	1.44 ± 0.001	3.29 ± 0.018	2.63 ± 0.035	3.65 ± 0.188	3.77 ± 0.016
HvMeOH	1.50 ± 0.044	NA	2.50 ± 0.014	5.59 ± 0.191	2.88 ± 0.051
HvAq	9.22 ± 0.527	NA	3.46 ± 0.012	13.39 ± 0.219	5.18 ± 0.078
OhEA	1.46 ± 0.016	3.81 ± 0.252	4.30 ± 0.057	4.92 ± 0.335	20.95 ± 0.581
OhMeOH	1.63 ± 0.018	NA	3.50 ± 0.069	5.51 ± 0.141	3.89 ± 0.097
OhAq	4.46 ± 0.024	NA	21.76 ± 1.357	11.84 ± 0.465	5.86 ± 0.050
VtEA	1.57 ± 0.003	3.15 ± 0.052	3.21 ± 0.012	2.07 ± 0.095	2.74 ± 0.044
VtMEOH	1.60 ± 0.008	NA	2.26 ± 0.010	4.21 ± 0.180	8.68 ± 0.214
VtAq	5.55 ± 0.080	NA	4.41 ± 0.145	13.74 ± 0.514	8.31 ± 0.355
Galantamine	0.002 ± 0.000	0.002 ± 0.001	ND	ND	ND
Kojic acid	ND	ND	0.14 ± 0.001	ND	ND
Acarbose	ND	ND	ND	1.00 ± 0.023	6.67 ± 0.200

Hv: Hedysarum varium; Oh: Onobrychis hypargyrea; Vt: Vicia truncatula; EA: ethyl acetate extract; MeOH: methanolic extract; Aq: aqueous extract. Values significantly () lower than the positive control. Values significantly () higher than the positive control.