Antileishmanial Effect of 5,3′-Hydroxy-7,4′-dimethoxyflavanone of Picramnia gracilis Tul. (Picramniaceae) Fruit: In Vitro and In Vivo Studies

Table 2

Blood levels of ALT, BUN, and creatinine in hamsters treated with 5,3′-hydroxy-7,4′-dimethoxyflavanone.

Group	ALT (U/L)	BUN (mg/dL)	Creatinine (mg/dL)
(A) TD0
Healthy ()	64.4 ± 5.6	15.9 ± 2.6	0.4 ± 0.1
Infected/untreated ()	73.9 ± 2.8	18.2 ± 1.9	0.4 ± 0.14
Flavanone solution ()	67.8 ± 3.2	18.0 ± 4.9	0.5 ± 0.1
Flavanone cream ()	65.8 ± 17.6	17.4 ± 1.3	0.3 ± 0.02
MA (i.l) ()	57.0 ± 6.1	20.9 ± 6.9	0.4 ± 0.1
(B) TD8
Flavanone solution ()	76.8 ± 3.7	20.0 ± 2.2	0.4 ± 0.03
Flavanone cream ()	77.1 ± 7.6	22.9 ± 6.4	0.3 ± 0.1
MA (i.l) ()	62.0 ± 8.5	23.8 ± 2.2	0.8 ± 0.1

Data represent the mean values ± SD of animals per group of treatment.