Pharmacokinetics of Immediate and Sustained Release Cephalexin Administered by Different Routes to Llamas (Lama glama)

Table 3

Time above MIC₉₀ ( > MIC) calculated for cephalexin following an intravenous (IV), intramuscular (IM), and subcutaneous (SC) 10 mg/kg injection to 6 llamas. Results (mean ± SD) are expressed in hours (h) and dosing interval (DI) percentage.

> MIC	Escherichia coli (8 µg/mL)			Coagulase-positive staphylococci (1 µg/mL)
	IV	IM	SC	IV	IM	SC
(h)	1.7 ± 0.1	2.3 ± 0.5	3.3 ± 0.3	3.6 ± 0.5	4.4 ± 0.8	7.1 ± 1.2
(% 6 h DI)	28.2	38.5	55.6	60.6	73.0	100.0
(% 8 h DI)	21.1	29.0	41.7	45.5	54.5	88.6