Cytotoxic Activity of Holothuria leucospilota Extract against Leishmania infantum In Vitro

Table 1

In vitro antileishmanial activity of H. leucospilota and reference drug Glucantime against L. infantum promastigotes and amastigotes in different time points.

Test sample/drug	Promastigotes			Survival (%)	Amastigotes
	(µg/mL)				(µg/mL)
	24 h	48 h	72 h	50 µg/mL	24 h	48 h	72 h
Body wall extract
Cuvierian organs	>1000	>1000	>1000	>1000	>1000	>1000	>1000
Coelomic fluid
Glucantime

Data are presented as the means SD of results from triplicate experiments.
Survival of promastigotes after 72 hours of exposure to 50 g/mL concentration of test compounds.