Antidiabetic Effects of the Ethanolic Root Extract of Uvaria chamae P. Beauv (Annonaceae) in Alloxan-Induced Diabetic Rats: A Potential Alternative Treatment for Diabetes Mellitus
Table 3
Effect of the root extract of U. chamae on other plasma biochemical parameters.
Parameters
Control (2% acacia)
Glibenclamide (71 µg/kg)
Pioglitazone (429 µg/kg)
UC (100 mg/kg)
UC (250 mg/kg)
UC (400 mg/kg)
Diabetic untreated
AST (U/L)
21.67 ± 4.26
30.33 ± 4.10
27.67 ± 4.63
23.0 ± 1.53
27.67 ± 2.03
26.67 ± 0.88
30.0 ± 1.16
ALT (U/L)
15.67 ± 1.33
26.67 ± 3.18
18.33 ± 4.49
19.33 ± 6.00
22.67 ± 3.18
24.33 ± 3.38
17.33 ± 2.03
ALP (U/L)
30.67 ± 5.70
30.67 ± 3.53
30.67 ± 4.18
21.00 ± 2.08
28.33 ± 6.49
28.00 ± 6.55
34.0 ± 6.66
Creatinine (mg/dl)
0.83 ± 0.03
1.00 ± 0.10
0.80 ± 0.10
1.03 ± 0.09
0.83 ± 0.03
0.80 ± 0.06
1.13 ± 0.03
Urea (mg/dl)
38.00 ± 7.02
39.67 ± 7.05
33.67 ± 4.81
32.00 ± 1.16
26.67 ± 3.48
34.0 ± 3.22
44.67 ± 5.36
Protein (g/dl)
6.90 ± 0.62
5.97 ± 0.54
6.73 ± 0.38
6.47 ± 0.58
6.13 ± 0.59
6.70 ± 0.38
6.97 ± 0.09
ALB (mg/dl)
3.40 ± 0.35
2.83 ± 0.38
3.73 ± 0.32
3.23 ± 0.30
3.03 ± 0.20
3.53 ± 0.29
3.20 ± 0.20
Significant difference (;) between the mean ± SEM of test groups vs. control. UC: Uvaria chamae.
