Antidiabetic Effects of the Ethanolic Root Extract of Uvaria chamae P. Beauv (Annonaceae) in Alloxan-Induced Diabetic Rats: A Potential Alternative Treatment for Diabetes Mellitus
Table 4
Effect of the root extract of U. chamae on body weight (g).
Days
Control (2% acacia)
Glibenclamide (71 µg/kg)
Pioglitazone (429 µ/kg)
UC (100 mg/kg)
UC (250 mg/kg)
UC (400 mg/kg)
Diabetic untreated
1
146.0 ± 0.57
124.0 ± 10.69
153.0 ± 4.04
139.3 ± 9.35
156.0 ± 6.81
124.7 ± 3.71
131.3 ± 4.18
3
144.7 ± 0.33
115.7 ± 4.80
152.0 ± 5.29
135.3 ± 7.42
154.3 ± 7.54
123.3 ± 3.33
130.0 ± 5.29
5
140.7 ± 2.33
119.7 ± 4.91
129.7 ± 1.86
111.7 ± 7.88
143.7 ± 7.3
119.0 ± 2.65
125.0 ± 2.89
7
144.0 ± 2.08
122.7 ± 5.90
131.0 ± 2.65
122.7 ± 3.71
143.7 ± 5.78
117.3 ± 1.76
119.3 ± 4.26
9
144.7 ± 2.67
118.3 ± 9.28
127.3 ± 2.91
113.7 ± 5.81
132.3 ± 6.69
114.7 ± 2.91
107.3 ± 4.06
11
145.0 ± 2.65
131.3 ± 7.69
127.3 ± 2.90
114.3 ± 3.48
109.7 ± 4.84
110.0 ± 2.65
115.3 ± 4.33
13
149.7 ± 3.18
132.0 ± 3.61
141.3 ± 2.60
112.3 ± 1.45
136.0 ± 5.69
107.0 ± 5.57
109.3 ± 3.71
15
155.0 ± 3.51
133.3 ± 1.76
141.7 ± 2.85
103.7 ± 2.33
137.3 ± 1.20
106.3 ± 8.95
116.0 ± 5.51
Significant difference (;) between the mean ± SEM of test groups vs. control. UC: Uvaria chamae.
