Antidiabetic Effects of the Ethanolic Root Extract of Uvaria chamae P. Beauv (Annonaceae) in Alloxan-Induced Diabetic Rats: A Potential Alternative Treatment for Diabetes Mellitus
Table 5
The effect of the root extract of U. chamae on the blood components.
Parameters
Control (2% acacia)
Glibenclamide (71 µg/kg)
Pioglitazone (429 µ/kg)
UC (100 mg/kg)
UC (250 mg/kg)
UC (400 mg/kg)
Diabetic untreated
WBC (×109/L)
6.9 ± 0.47
11.9 ± 1.22
9.6 ± 0.70
5.2 ± 0.36
6.4 ± 0.56
6.3 ± 0.64
9.17 ± 0.61
RBC (×1012/L)
5.8 ± 0.30
5.2 ± 0.26
5.8 ± 0.50
5.5 ± 0.90
6.0 ± 0.48
5.8 ± 0.31
6.3 ± 0.62
Hgb (g/dl)
12.0 ± 0.6
10.0 ± 0.43
10.3 ± 0.79
10.0 ± 1.64
10.8 ± 0.8
10.0 ± 0.12
12.4 ± 1.69
PCV (%)
40.3 ± 3.38
29.9 ± 0.67
30.23 ± 2.10
32.0 ± 5.74
32.9 ± 2.64
32.8 ± 1.48
38.10 ± 5.29
MCV (fL)
70.5 ± 7.0
54.6 ± 2.24
56.0 ± 2.52
58.4 ± 2.17
55.3 ± 2.95
59.3 ± 4.33
60.2 ± 3.23
MCH (pg)
20.9 ± 1.29
19.3 ± 0.70
17.9 ± 0.23
18.4 ± 0.43
18.0 ± 0.94
18.5 ± 0.67
19.5 ± 0.92
MCHC (g/dl)
30.0 ± 1.30
33.3 ± 0.67
34.0 ± 0.35
31.3 ± 0.64
32.8 ± 0.03
32.2 ± 1.58
32.5 ± 0.30
PLT (×109/L)
918.7 ± 5.90
944.0 ± 25.74
958.0 ± 34.70
971.3 ± 8.99
967.7 ± 22.60
929.0 ± 17.04
955.0 ± 26.63
Significant difference (;) between the mean ± SEM of test groups vs. control. UC: Uvaria chamae.
