TY - JOUR A2 - Rashid, Mohammad A. AU - Abu Bakar, Fazleen Izzany AU - Abu Bakar, Mohd Fadzelly AU - Abdullah, Norazlin AU - Endrini, Susi AU - Rahmat, Asmah PY - 2018 DA - 2018/07/09 TI - A Review of Malaysian Medicinal Plants with Potential Anti-Inflammatory Activity SP - 8603602 VL - 2018 AB - This article aims to provide detailed information on Malaysian plants used for treating inflammation. An extensive search on electronic databases including PubMed, Google Scholar, Scopus, and ScienceDirect and conference papers was done to find relevant articles on anti-inflammatory activity of Malaysian medicinal plants. The keyword search terms used were “inflammation,” “Malaysia,” “medicinal plants,” “mechanisms,” “in vitro,” and “in vivo.” As a result, 96 articles on anti-inflammatory activity of Malaysian medicinal plants were found and further reviewed. Forty-six (46) plants (in vitro) and 30 plants (in vivo) have been identified to possess anti-inflammatory activity where two plants, Melicope ptelefolia (Tenggek burung) and Portulaca oleracea (Gelang pasir), were reported to have the strongest anti-inflammatory activity of more than 90% at a concentration of 250 µg/ml. It was showed that the activity was mainly due to the occurrence of diverse naturally occurring phytochemicals from diverse groups such as flavonoids, coumarins, alkaloids, steroids, benzophenone, triterpenoids, curcuminoids, and cinnamic acid. Hence, this current review is a detailed discussion on the potential of Malaysian medicinal plants as an anti-inflammatory agent from the previous studies. However, further investigation on the possible underlying mechanisms and isolation of active compounds still remains to be investigated. SN - 2633-4682 UR - https://doi.org/10.1155/2018/8603602 DO - 10.1155/2018/8603602 JF - Advances in Pharmacological Sciences PB - Hindawi KW - ER -