Hydroethanolic Stem Bark Extract of Burkea africana Attenuates Vincristine-Induced Peripheral Neuropathy in Rats

Figure 2

Effect of BAE (50–1000 mg kg⁻¹ p.o.) and pregabalin (PGABA) (10–100 mg kg⁻¹ p.o.) on the vincristine-induced intermediate hyperalgesia in rats (von Frey 9 g). (a, b) The time-course effect; (c, d) the bar graphs of the AUCs. ; ; ; compared with vehicle-treated group (2-way RM ANOVA followed by Dunnett’s post hoc test). ; ; ; compared with the vehicle-treated group (ordinary 1-way ANOVA followed by Turkey’s post hoc test). Each data presented are mean ± S.E.M (n = 10).

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