Antimicrobial Potential of Streptomyces spp. Isolated from the Rift Valley Regions of Ethiopia

Table 3

The antimicrobial activity (mm) of the isolates against bacterial pathogens during secondary screening.

S.No.	Test pathogens
	Isolates code	Gram-negative bacteria					Gram-positive bacteria		Fungi
		Ec	Kp	Pa	St1	St2	Sa	Se	A. niger
1	RVE002	19 ± 0.6^i	12 ± 0.0^de	16 ± 0.6^g	15 ± 0.0^fg	12 ± 0.6^ef	22 ± 0.0^g	19 ± 1.0^k	22 ± 1.2^j
2	RVE004	5 ± 0.0^b	0 ± 0.0^a	18 ± 1.2^f	13 ± 1.2^de	0 ± 0.0^a	9 ± 1.0^cd	8 ± 0.0^bc	17 ± 0.6^h
3	RVE029	0 ± 0.0^a	10 ± 0.6^cd	14 ± 0.0^c	7 ± 0.0^b	12 ± 0.6^ef	17 ± 0.0^f	24 ± 0.6^l	16 ± 0.0^h
4	RVE077	17 ± 0.0^h	12 ± 0.6^de	9 ± 0.0^b	15 ± 0.6^fg	18 ± 0.6^h	14 ± 1.2^e	0 ± 0.0^a	9 ± 0.0^ef
5	RVE116	15 ± 1.2^g	14 ± 0.0^f	16 ± 0.0^de	6 ± 2. 3^b	0 ± 0.0^a	7 ± 0.0 ^c	9 ± 0.0^cd	8 ± 0.0^ef
6	RVE118	7 ± 0.0^c	9 ± 1.0^c	14 ± 0.6^c	11 ± 0.0^cd	12 ± 0.6^ef	17 ± 0.0 ^f	17 ± 1.0^j	5 ± 0.0^b
7	RVE125	19 ± 0.0^i	14 ± 0.0^f	9 ± 0.6^b	11 ± 0.0^cd	9 ± 0.6^c	21 ± 0.6^g	14 ± 0.0^gh	9 ± 0.0^ef
8	RVE129	21 ± 0.6^jk	25 ± 0.0^j	20 ± 0.0^h	18 ± 0.0^gh	18 ± 0.0^h	27 ± 0.0^i	22 ± 0.0^l	22 ± 0.6^j
9	RVE133	0 ± 0.0^a	17 ± 1.0^g	20 ± 0.0^h	17 ± 0.6^gh	0 ± 0.0^a	12 ± 1.2^cd	10 ± 0.6^cd	12 ± 0.6^g
10	RVE144	0 ± 0.0^a	10 ± 1.0^cd	9 ± 0.0^b	0 ± 0.0^a	0 ± 0.0^a	15 ± 1.0 ^f	16 ± 1.0^h	16 ± 0.3^h
11	RVE165	12 ± 0.0^de	17 ± 0.6^g	16 ± 0.6^de	11 ± 0.0^cd	14 ± 0.6^fg	11 ± 0.0^cd	14 ± 0.0^g	10 ± 1.2^g
12	RVE172	0 ± 0.0^a	10 ± 0.0^cd	14 ± 0.6^c	0 ± 0.0^a	0 ± 0.0^a	19 ± 0.0^g	19 ± 1.0^j	5 ± 0.0^b
13	RVE187	25 ± 0.6^l	27 ± 0.0^k	22 ± 0.0^h	20 ± 1.2^i	21 ± 0.0^i	25 ± 1.2^h	25 ± 0.6^l	16 ± 0.3^h
14	RVE193	22 ± 1.2^k	15 ± 1.0^fg	18 ± 0.0^f	8 ± 0.0^c	9 ± 0.6^c	11 ± 0.6^cd	13 ± 0.0^f	9 ± 0.6^ef
15	RVE194	15 ± 1.2^g	13 ± 0.0^f	15 ± 1.2^cd	20 ± 0.6^i	21 ± 0.6^i	12 ± 1.0^e	19 ± 1.0^j	17 ± 1.2^i
16	RVE214	7 ± 0.6^c	11 ± 0.6^de	14 ± 0.6^c	7 ± 0.6^b	14 ± 0.0^fg	5 ± 1.0^b	11 ± 1.0^e	17 ± 0.6^i
17	RVE217	19 ± 0.0^i	25 ± 0.6^j	18 ± 0.6^f	22 ± 1.2^j	18 ± 0.0^h	26 ± 0.6^i	25 ± 0.0^l	16 ± 0.0^h
18	RVE219	13 ± 0.0^ef	8 ± 0.6^c	14 ± 1.0^c	8 ± 2.3^c	8 ± 0.6^b	7 ± 0.6^b	15 ± 0.6^h	18 ± 0.0^i
19	RVE226	13 ± 0.6^ef	8 ± 1.0^c	9 ± 1.2^b	0 ± 0.0^a	11 ± 0.6^cde	5 ± 1.0^b	0 ± 0.0^a	11 ± 0.3^g
20	RVE227	20 ± 0.0^jk	22 ± 0.0^i	18 ± 0.6^f	15 ± 0.0^fg	18 ± 0.6^h	15 ± 1.2^f	10 ± 0.6^cd	5 ± 0.0^b
21	RVE234	14 ± 0.6^g	15 ± 0.0^fg	17 ± 0.6^d	18 ± 0.6^gh	18 ± 0.0^h	21 ± 0.6^g	22 ± 0.0^k	10 ± 0.0^fg
22	RVE239	17 ± 0.0^h	16 ± 1.0^g	15 ± 0.0^cd	20 ± 0.0^i	14 ± 0.6^fg	15 ± 0^f	18 ± 0.0^i	9 ± 0.0^ef
23	RVE247	12 ± 0.6^de	14 ± 0.6^f	8 ± 0.0^b	10 ± 0.0^c	14 ± 0.6^fg	15 ± 0.6^f	16 ± 1.0^h	11 ± 1.2^g
24	RVE248	11 ± 1.2^cd	14 ± 0.0^f	12 ± 0.6^de	10 ± 1.2^c	9 ± 0.6^c	17 ± 1.2^h	15 ± 0.6^h	16 ± 0.0^h
	Control drug	28 ± 0.58^m	25 ± 0.8^j	24 ± 0.58^i	29 ± 0.58^k	28 ± 0.3^j	25 ± 0.58^h	25 ± 0.8^l	29 ± 0.6^k
	Negative control	0 ± 0.0^a	0 ± 0.0^a	0 ± 0.0^a	0 ± 0.0^a	0 ± 0.0^a	0 ± 0.0^a	0 ± 0.0^a	0 ± 0.0^a

Note: Sa: Staphylococcus aureus; Se: Staphylococcus epidermidis; St1: Salmonella typhi ATCC-13311; Kp: Klebsiella pneumoniae; Ec: Escherichia coli; St2: Salmonella typhi ATCC-14028; Pa: Pseudomonas aeruginosa. Mean values sharing the same superscripts within a column are not significantly different at ; inhibition zone diameters are expressed as mean ± SD of the three replications.