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Drug Repurposing: Mining New Therapeutic Options for Non-Communicable Diseases

Call for Papers

Translational research entails collaborative scientific endeavours with the ultimate goal of putting investigative findings in the basic medical sciences into useful application in clinical practice for the purpose of prevention, diagnosis, and therapeutic management of disease conditions. Drug repurposing or repositioning refers to engagements to put to new therapeutic uses currently approved drugs, agents previously withdrawn due to possible fatal deleterious effects, and relatively outdated drugs for entirely new medical indications. The incidence, morbidity, and mortality associated with noncommunicable diseases (NCDs) have been on the increase worldwide over the years. Major contributors to the burden of NCDs in both developing and developed countries include cardiovascular diseases, chronic respiratory diseases, cancers, diabetes, and mental illnesses. In most cases, cures are unavailable and current palliative therapeutic interventions are associated with worrisome untoward effects. Translational research and drug repurposing offer great opportunity for widening the therapeutic options for the treatment of NCDs. The advantages over the usual drug discovery and development pipeline include lower associated risk as well as conservation of time and cost.

The aims of this special issue are to provide the platform for researchers and collaborative research teams to share their findings from translational and drug repurposing investigative engagements as regards NCDs and to showcase potential leads and alternate therapeutic options towards reducing the burden of NCDs worldwide.

Potential topics include but are not limited to the following:

  • Reviews on translational research and drug repurposing related to NCDs
  • Translational research and drug repurposing research reports on the findings of in silico, in vitro, in vivo, or combination experimentation thereof as regards cardiovascular diseases, chronic respiratory diseases, cancers, diabetes, mental illnesses, and so on
  • Relevant reviews and research reports on rare, acute, and neglected diseases

Authors can submit their manuscripts through the Manuscript Tracking System at

Submission DeadlineFriday, 15 June 2018
Publication DateNovember 2018

Papers are published upon acceptance, regardless of the Special Issue publication date.

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